(MAH-noh-uh-MEEN OK-sih-days in-HIH-bih-ter) A type of drug used to treat depression. It stops the breakdown of certain chemicals in the brain that help improve a person's mood. A monoamine oxidase inhibitor is a type of antidepressant. Also called MAO inhibitor.... read more ›
Since then, other classes of drugs, like selective serotonin reuptake inhibitors (SSRIs), have become more popular treatment choices, because MAOIs tend to have more side effects and require dietary restrictions. Nowadays, doctors typically prescribe MAOIs only when other medications have been unsuccessful.... view details ›
|Drug Name||Avg. Rating||Reviews|
|Nardil (Pro) Generic name: phenelzine||8.3||112 reviews|
|Parnate (Pro) Generic name: tranylcypromine||8.5||89 reviews|
|Emsam (Pro) Generic name: selegiline||7.5||47 reviews|
|Marplan (Pro) Generic name: isocarboxazid||9.0||6 reviews|
Monoamine oxidase inhibitors (MAOIs) are a separate class from other antidepressants, treating different forms of depression and other nervous system disorders such as panic disorder, social phobia, and depression with atypical features.... continue reading ›
Mao Zedong (26 December 1893 – 9 September 1976), also known as Chairman Mao, was a Chinese communist revolutionary who was the founder of the People's Republic of China (PRC), which he led as the chairman of the Chinese Communist Party from the establishment of the PRC in 1949 until his death in 1976.... see details ›
Several lines of evidence indicate that monoamine oxidase (MAO) activity can regulate levels of biogenic amines and neuronal activity in the nervous system. The two types of MAO activity, A and B, appear to have different domains of activity in the body.... see more ›
Today, even though MAOIs continue to be effective in treating depression, their use has declined because of newer antidepressant medications that have fewer side effects and do not have strict dietary restrictions. MAOIs are, however, still a good option for some people when other treatments have failed.... read more ›
Side effects of MAOIs
Nausea, diarrhea or constipation. Headache. Drowsiness. Insomnia.... see details ›
Monoamine oxidase inhibitors (MAOIs) are an extremely strong class of antidepressants that treat depression by preventing the breakdown of the brain chemicals serotonin, dopamine, and norepinephrine. This helps them do their work of regulating your mood.... continue reading ›
What drugs interact with MAOIs? MAO inhibitors should be avoided with other antidepressants such as paroxetine fluoxetine, amitriptyline, nortriptyline, bupropion; pain medications like methadone, tramadol, and meperidine; dextromethorphan, St. Johns Wort, cyclobenzaprine, and mirtazapine.... continue reading ›
Is Xanax An MAOI? Monoamine oxidase inhibitors (MAOI) were the first antidepressant medications created. They are not as commonly used today but they are still effective medications. Xanax is not an antidepressant medication and is not in the class of MAOI drugs.... view details ›
The four most commonly prescribed MAOIs are selegiline, isocarboxazid, phenelzine, and tranylcypromine.... read more ›
- Monoamine oxidases. ...
- Plants containing monoamine oxidases inhibitor (MAOI) ...
- Syrian rue (Peganum harmala) ...
- Yagé (Banisteriopsis caapi vine) ...
- Passionflower (Passiflora incarnata) ...
- Nutmeg (Myristica fragrans) ...
- Licorice (Glycyrrhiza glabra) ...
- Fragrant ginger/galangal (Kaempferia galangal)
However, there are a few dangerous and potentially severe side effects associated with MAOIs: Muscle spasms. Reduced libido and inability to reach orgasm. Low blood pressure.... see more ›
Monoamine oxidase inhibitors (MAOI's) have been shown to be significantly superior to placebo in the treatment of some anxiety disorders, particularly agoraphobia and mixed anxiety--depressive states.... see more ›
- Obey orders in all your actions.
- Don't take a single needle or piece of thread from the masses.
- Turn in everything captured.
How did Mao gain support of the peasantry? What did he promise? *he insisted that Communist forces treat the peasants fairly and politely. They paid peasants for the food their forces required to help Mao's army grow.... continue reading ›
The three principles are often translated into and summarized as nationalism, democracy, and the livelihood of the people.... continue reading ›
A number of factors may lead to elevated MAO-A level or activity, including glucocorticoid administration, estrogen depletion and mitochondrial toxicity/dysfunction (Fitzgerald et al, 2007; Ou et al, 2006a; Sacher et al, 2010).... see details ›
The name "Mao suit" comes from Chinese Communist Mao Zedong's fondness for the style. The garment became closely associated with him and with Chinese Communism. Mao's cut of the suit was further influenced by the Stalin tunic then prevalent among Soviet officials.... see details ›
Studies in humans and mice found that heavy alcohol consumption increases MAOA levels and activity in a brain region involved in complex cognitive processes, possibly contributing to the effects of high-activity MAOA variants [255, 256].... view details ›
In this paper, "ready to drink" coffee brews exhibited inhibitory properties on recombinant human MAO A and B isozymes catalyzing the oxidative deamination of kynuramine, suggesting that coffee contains compounds acting as MAO inhibitors.... read more ›
Tricyclic and tetracyclic antidepressants, also called cyclic antidepressants, are among the earliest antidepressants developed. They're effective, but they've generally been replaced by antidepressants that cause fewer side effects.... see more ›
The irreversible MAOIs are rapidly absorbed and generally quickly eliminated, with plasma elimination half-lives of 1.5–4 hours. However, because of their irreversible inhibition of MAO, the physiological effects of phenelzine, isocarboxazid, and tranylcypromine persist for up to 2–3 weeks.... see details ›
Chocolate, red wine, and antidepressants.
Along with many beers, aged cheeses, processed meats, and smoked fish, chocolate and red wine contain an amino acid derivative called tyramine. Mixing tyramine with monoamine oxidase inhibitors (MAOIs) such as selegiline and phenelzine can cause unsafe spikes in blood pressure.... view details ›
Although SSRIs are the current frontline treatment for depression, monoamine oxidase inhibitors (MAOIs) were the first antidepressants developed. They are typically more potent than SSRIs because they affect more neurotransmitters, and they can cause more side effects.... see details ›
MAO-A inhibition reduces the breakdown of primarily serotonin, norepinephrine, and dopamine; selective inhibition of MAO-A allows for tyramine to be metabolised via MAO-B.... continue reading ›
High caffeine intake, when combined with monoamine oxidase (MAO) inhibitor therapy, can lead to severe hypertension, according to a research letter in the Annals of Internal Medicine.... see more ›
It is safe to eat chocolate. While taking MAOIs it is even more important than usual to eat food which is as fresh as possible and to handle food safely. Store all protein food (meat, fish, dairy) in a fridge. Remember, leaflets like this can only describe some of the effects of medication.... read more ›
Conclusion: Pizzas from large chain commercial outlets are safe for consumption with MAOIs. However, caution must be exercised if ordering pizzas from smaller outlets or gourmet pizzas known to contain aged cheeses. All soybean products should be avoided, especially soy sauce and tofu.... read more ›
The S-enantiomer of omeprazole, esomeprazole, has recently also been described as an inhibitor of monoamine oxidase-A (MAO-A), the main enzyme responsible for 5-HT degradation, albeit with lower potency compared to the effect on TPH1 and TPH2.... view details ›
Trazodone has a unique chemical structure and is unrelated to selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), or monoamine oxidase inhibitors (MAO inhibitors).... read more ›
Bupropion was originally classified as an "atypical" antidepressant because it does not exert the same effects as the classical antidepressants such as Monoamine Oxidase Inhibitors (MAOIs), Tricyclic Antidepressants (TCAs), or Selective Serotonin Reuptake Inhibitors (SSRIs).... continue reading ›
BASEL, SwitzerlandA specialty oregano extract may support mood, serving as a monoamine reuptake inhibitor, according to a new study (Br J Nutr.... see more ›
Phenelzine (Nardil) has been the MAOI most researched for the treatment of panic. Another MAOI that may be effective against panic attacks is tranylcypromine (Parnate). Possible Benefits. Helpful in reducing panic attacks, elevating depressed mood, and increasing confidence.... view details ›
While Δ1-THC and hashish extract inhibited MAO activity. to an extent varying according to the substrate, CBD was innocuous or only slightly inhibitory—in correspondence with the psychomimetic potency. Phospholipids associated with MAO were essential for the inhibition of the oxidase activity by Δ1-THC.... continue reading ›
Xanax is also used to treat panic attacks. Lexapro and Xanax belong to different drug classes. Lexapro is a selective serotonin reuptake inhibitor (SSRI) and Xanax is a benzodiazepine.... view details ›
A number of factors may lead to elevated MAO-A level or activity, including glucocorticoid administration, estrogen depletion and mitochondrial toxicity/dysfunction (Fitzgerald et al, 2007; Ou et al, 2006a; Sacher et al, 2010).... see more ›
MAO is located on the outer membranes of mitochondria and thus, in brain, is present primarily in nerve terminals and glia. In the periphery, MAO is found in particularly high concentrations in liver and kidney.... continue reading ›
Physical activity plays a complex regulatory role in the activity of dopamine, norepinephrine, and serotonin. Moderate exercise causes an overall increase in monoamine transmission that improves brain function, motivation, and adaptation to exercise [248, 189].... see details ›
Following release, 5-HT receptor activation and reuptake by 5-HT transporter (5-HTT), serotonin is degraded by MAO (monoamine oxidase) and ALDH (aldehyde dehydrogenase) into 5-hydroxyindole-3-acetic acid (5-HIAA).... continue reading ›
Mutations in the MAOA gene cause monoamine oxidase A deficiency. This condition affects males almost exclusively and is characterized by mild intellectual disability and behavioral problems, including aggressive and violent outbursts. In some cases, particular foods seem to worsen symptoms of the condition.... see details ›
Those activities during and after the physical exercise have different tendency in each other enzyme. MAO-A activity was sharply decreased with stress by physical activities compared to the normal group, whereas MAO-B activity was increased for 60 minutes after exercise.... view details ›
- Sleepiness, or trouble getting to sleep.
- Dizziness, lightheadedness, and fainting.
- Dry mouth, blurred vision, and appetite changes.
- High or low blood pressure.
- Changes in heart rate and rhythm.
Between the two types of MAO, MAO-B has been believed to be involved in dopamine degradation, which supports the idea that the therapeutic efficacy of MAO-B inhibitors in Parkinson's disease can be attributed to an increase in extracellular dopamine concentration.... read more ›
Monoamine oxidases (MAOs) are oxidoreductases that deaminate catecholamines. In dopaminergic axons, released dopamine (DA) is taken up from the extracellular space, where it is recycled into vesicles or degraded by MAO. The biological rationale for cytosolic DA metabolism is unknown.... see details ›
Key findings: Caffeine acts as a MAO inhibitor with Ki values of 0.70 mM and 3.83 mM for the inhibition of MAO-A and MAO-B, respectively. The results show that caffeine binds reversibly and competitively to both MAO enzymes.... read more ›
Recent discoveries of specific MAO-A inhibitory activity of traditionally used herbal remedies include Acorus gramineus (Tao et al., 2005), Rhazya stricta (Ali et al., 1998), Zanthoxylum schinifolium (Jo et al., 2002) and Kaempferia galangal (Huong et al., 2002).... see details ›
Methylphenidate is a monoamine-reuptake inhibitor, which has functional agonistic effects resembling psychostimulants, and is marketed for the treatment of ADHD and attention deficit disorder.... view details ›
Is Xanax An MAOI? Monoamine oxidase inhibitors (MAOI) were the first antidepressant medications created. They are not as commonly used today but they are still effective medications. Xanax is not an antidepressant medication and is not in the class of MAOI drugs.... read more ›